Download Biomolecular Imaging at High Spatial and Temporal Resolution by Thomas Harry Sharp PDF

By Thomas Harry Sharp

As a part of a collaboration among various teams in chemistry and biochemistry, Thom Sharp offers right here his thesis paintings at the improvement of latest equipment for cryoelectron microscopy. all through his Ph.D., Thom needed to grasp a complete diversity of strategies together with modelling, molecular biology and microscopy. utilizing those abilities to take on an excellent challenge, the pursuit of high-resolution constructions of peptide-based fabrics, Thom highlights during this thesis his newly constructed equipment for analysing and processing this actual form of electron microscopy info. This thesis supplies the 1st molecular description of a de-novo designed peptide-based fabric. in most cases, this study can have a huge effect at the peptide meeting box, and likewise in electron microscopy because it introduces new equipment and techniques, all of that are Thom's innovations and are defined during this thesis.

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